Model alignment of anthrax attack simulations

This paper describes our experience aligning two simulation models of disease progression after biological attacks. The first model is the Incubation-Prodromal-Fulminant (IPF) model, a variation of the Susceptible-Infected-Recovered (SIR) epidemiological model, and the second is an agent-based model called BioWar. We run BioWar simulations to see whether the results will, at the population level, match the IPF results. This process provides information not only about the level of validation; but identifies the areas to improve the agentbased model. This study provides insights for modelers who are developing simulation tools for investigating bioattacks and for decision makers who use these tools.